Betelnut to be avoided
The study highlights the need for better education on the harms of this popular stimulant in a part of the world where both the habit and diabetes are on the rise. While the habit of chewing betel quid is common to Asian and Western Pacific countries.
Risks associated with betel-quid chewing as compared with nonuse were significantly increased for cardiovascular disease, all-cause mortality, obesity, metabolic syndrome, diabetes, hypertension, hypertriglyceridemia, and chronic kidney disease.
Betel/areca nut contains four arecal alkaloids, and their nitrosated compounds are known to be carcinogenic. World Health Organization has deemed betel-quid chewing a risk factor for oral and esophageal cancer.
Betel nut also contains substances that appear to increase the release of inflammatory mediators and reactive oxygen species that have the potential to cause chronic inflammation, hypothesized to play a role in the development of both diabetes and coronary disease.
Arecoline, found in betel quid, may promote appetite and potentially alter insulin secretion. Other neurological effects have also been proposed, linking betel-quid use to increases in heart rate and altered hemodynamics.
All of these potential mechanisms need to be studied in more detail. more