Diabetes and kidney disease
the exact phenomenon is not really know. there are theories as to what may happen. but the theories are definitely there. i will try to explain it in as simple a form as possible.
diabetes is a very common, and probably the commonest cause of kidney disease.
what really happens is that extra sugar in the blood, called hyperglycemia in the medical parlance causes changes in cells of the body. the damaged cells are shed and get stuck in the small filters in the kidneys, filters meant for filteration of blood to form urine.
now these cells need to be cleared. so the antibodies and the cells that fight infection accumulate to clear these cells. now when they work, the cause damage to the surrounding area too, something like damage caused by a bulldozer to the road around the earth it digs.
and this may cause kidney disease. please note this is a very brief and simplified explanation of a detailed and long process.
Now one needs to understand that diabetes is almost always undiagnosed for a long time. so this damaging process in on for a long time. once the sugars are controlled, the process abates, but it compromises the function of the kidney. and so further insult in the form of painkillers, hypotension, severe infection (sepsis) may cause damage and make a person seriously ill.
Now for the double edged sword. some of the medicines that are given for diabetes may actually cause some damage too. but this is usually less so.
I hope you find that useful
Dr Saumya Mittal
Physician and Diabetician
9873711878 more