1. A HALO nipple aspirate fluid examination allows the detection of benign breast disease, and the attendant increase in relative risk of developing breast cancer, years before an abnormality becomes visible by imaging or becomes a palpable lesion. A smart blood test developed by scientists dramatically slows the spread breast cancer, scientists have revealed. 2.ESRI The new test, developed by experts in London, spots when the most common form of breast cancer has stopped responding to standard treatments. It then tells doctors exactly which drug to treat patients with next, matching the treatment to the genetic make-up of the tumour. Trials carried out by the Institute of Cancer Research and the Royal Marsden hospital in London found that by using the tests, and then moving patients onto a drug matched to its genetic make-up, doctors were able to halt the progress of breast cancer for six months. Women who were treated with a drug that had not been DNA matched only had two and a half months before the tumour started spreading again. Some 54,000 women are diagnosed with breast cancer in the UK each year, and 11,700 die with the disease annually. Researchers analysed blood samples from 783 women with oestrogen receptor positive breast cancer - the most common form of the disease, accounting for three quarters of cases. By using the test, scientists identified a single gene called ESR1, which mutates when a breast tumour has stopped responding to standard hormone treatment. more
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By Ramakant Dwivedi
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