metabolic acidosis is altogether a different terminology vis a vis other terms you mentioned , acid reflux or reflux esophagitis or achlasia cardia is also known as gerd or gastro esophageal reflux disease or disorders, it has to do with reduction of tone of esophageal sphincter(muscular guard at the junction of stomach n food pipe)which prevents leaking of food back to food pipe from stomach, it shows mild to severe episodes of pain or burning in the central chest or may simulate pain found in IHD/CAD(heart diseases) ie angina pectoris , or this pain may radiate to back of chest where it may be mistaken for skeletal pain /or vertebral spondylosis , but most of this come after few minutes to 1 hour after having eaten, sometimes continuous leaking of food may result into corrosion of food pipe resulting into chest discomfort , an advance condition called barretts esophagus may crop up from chronic esophagitis(inflammation of esophagus or food pipe), acid peptic disease or acid dyspepsia may be consequent upon longstanding GERD or it may be simultaneously occuring disorder, long term acidity resulting from loss of stomach buffering mechanism , lowering of ph of the stomach milieu, disturbance in prostaglandin mechanism, all or one of them may make lining of stomach more vulnerable to strong acidic environment present causing gastritis , this may range from mild gastritis , gastric erosion to full fledged gastric ulcer s. taking excessive pain killers (more or so cox 1 inhibitors like bruffen,aspirin pcm etc) may also induce such lesions. whereas metabolic acidosis means there is lowering of ph in blood and tissues , acedemia means lowering of PH in blood,mostly blood is maintained at 7.4 , if this goes below 7.1 there are higher chances of patients death ,cardiac arrhythmmia ,hypotension and in long term rhabdomyolysis(dissolution of muscles ) , acidosis means blood and tissue buffering is either hampered or overhelmed due to production of H+ (apart from k+/na+),normally there are 2 main anions or negative ions in body it is hco3-(carbonates) or cl-(chloride), metabolic acidosis may occur in renal tubular necrosis,long term kidney failure ,diarrhoea and vomiting etc ketoacidosis (one type of acidosis)of of type diabetes is very common cause of manageable emergency in setting of DM(diabetes mellitus).lactic acidosis is also one of the common causes predisposing to metabolic acidosis. hope this will be useful ,good luck
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